The ESRC:
Shortlisting your one percent...About us
We are the UK's largest organisation for funding research on economic and social issues. We support independent, high quality research which has an impact on business, the public sector and the third sector.
This is the Economic and Social Research Council –
Dynamics of Cardiovascular Ageing
- Start date: 01 October 2009
- End date: 30 March 2012
The aim of the research is to establish whether physiological aging can be assessed, noninvasively, by the analysis of cardiovascular signals, eg oscillations in blood flow.
A cohort of 80 healthy subjects from a wide and evenly distributed age range will be recruited for measurements. Their signals will be recorded and analysed using state-of-the-art nonlinear methods in order to quantify any age-related changes that occur. The lower-frequency oscillations known to be related to the activity of the endothelium, the inner lining of all the blood vessels, will be investigated in detail. Endothelial function declines with age, and diseases such as heart failure and hypertension have associated endothelial dysfunction.
The project will thus establish a baseline for endothelial processes in healthy individuals, as a function of age. The interest will be centered on finding out how the oscillatory amplitudes and interaction parameters change during ageing, including in the oldest old. It will also examine age-related changes in the dynamics of thermoregulation and blood oxygenation levels.
It is expected that the work will pave the way to a noninvasive method of establishing the level of endothelial reactivity in older people, potentially suitable as a routine diagnostic tool in general healthcare practice.
Impacts & reports
Dynamics of Cardiovascular Ageing
Author: Aneta Stefanovska Date: 08 May 2013 Impact Report
Author: Aneta Stefanovska Date: 08 August 2012 End of Grant Report
Outputs
Basal sympathetic activity to the microcirculation in tetraplegic man revealed by wavelet transform of laser Doppler flowmetry
Author: A. Bernjak Date: 25 June 2012 Journal article
Nonlinear dynamics of cardiovascular ageing
Author: Y. Shiogai Date: 25 June 2012 Journal article
- Lancaster University |
This is the to-die-for tool that has
to be on every EoL to-die-for Xmas list!
Everything else is redundant. This is all
you need. This is the ultimate find your 1% tool that puts all else in the
pale.
This is The Mirror –
A laser that predicts when you are going to die has been invented by scientists.
The beam is painless and can also be used to test for diseases including cancer and dementia.
It comes in a wrist watch-style device that analyses tiny cells inside the capillaries – the smallest blood vessels – to work out how quickly the body will age.
Grades, rated from 0, meaning death, to 100, equalling optimum function, are then used by scientists to calculate how long a person has left to live.
It has been patented by Aneta Stefanovska and Peter McClintock, physics professors from Lancaster University.
No more ‘Surprise Questions’…
By measuring the oscillations within the cells, the scientists say they can calculate the length of time before death and also test for diseases including cancer and dementia.
The result is graded from 0 for death to 100 for optimum functioning with the predictions becoming more accurate as more data is added.
The test was developed by two physics professors from Lancaster University, Aneta Stefanovska and Peter McClintock, with the help of grants from medical charities and government research bodies.
Professor Stefanovska is credited with inventing the method of analysing endothelial reactivity.
‘I am hoping we will build a database that will become larger and larger, so every person person measured can be compared against it,’ she said.No more SPICT…
- Metro
Everything that goes on in your cardiovascular system, whether you are going to have a stroke or heart attack, starts off as something going wrong in the endothelium.
“It also produces all sorts of chemicals that affect the rest of the tissue.
“It is a major organ, but people just don’t appreciate that.”
- Gulfnews
No more GSF…
The wrist watch-like contraption, which has been called the ‘death test’ watch, measures vital cells inside your capillaries. Those cells produce chemicals that identify what’s going wrong with your body, including whether you’ll have a stroke, a heart attack, or dementia. The watch can also tell you if you have cancer and how fast your body is aging- Fox NewsNo more waiting at the cemetery gate!
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